By comparison, glibenclamide blocks KATP channels from pancreatic B-cells in the nanomolar concentration range and this high affinity is at least partially explained by the slow dissociation of glibenclamide from the receptor (Zünkler et al. 1988a). (Quelle: bmb+f Forschungslandkarte Deutschland 1998)
Thus, temperature seems to affect both the extent of cromakalim-induced channel openings and the rate of dissociation of cromakalim from the target site. (Quelle: bmb+f Forschungslandkarte Deutschland 1998)
Key words: scapholunate dissociation, carpal ligament lesions, carpal instability, arthroscopy of the wrist (Quelle: Der niedergelassene Chirurg 1998)